Intermolecular and low-frequency intramolecular Raman scattering study of racemic ibuprofen

J J Lazarević; S Uskoković-Marković; M Jelikić-Stankov; M Radonjić; D Tanasković; N Lazarević; Z V Popović

doi:10.1016/j.saa.2014.01.135

Intermolecular and low-frequency intramolecular Raman scattering study of racemic ibuprofen

Spectrochim Acta A Mol Biomol Spectrosc. 2014 May 21:126:301-5. doi: 10.1016/j.saa.2014.01.135. Epub 2014 Feb 12.

Authors

J J Lazarević¹, S Uskoković-Marković², M Jelikić-Stankov², M Radonjić³, D Tanasković³, N Lazarević⁴, Z V Popović⁴

Affiliations

¹ Innovation center, Faculty of Technology and Metallurgy, University of Belgrade, Serbia. Electronic address: jasmina.lazarevic@hotmail.com.
² Faculty of Pharmacy, University of Belgrade, Serbia.
³ Scientific Computing Laboratory, Institute of Physics Belgrade, University of Belgrade, Pregrevica 118, 11080 Belgrade, Serbia.
⁴ Center for Solid State Physics and New Materials, Institute of Physics Belgrade, University of Belgrade, Pregrevica 118, 11080 Belgrade, Serbia.

PMID: 24608014
DOI: 10.1016/j.saa.2014.01.135

Abstract

We report the low-temperature Raman scattering study of racemic ibuprofen. Detailed analysis of the racemic ibuprofen crystal symmetry, related to the vibrational properties of the system, has been presented. The first principle calculations of a single ibuprofen molecule dynamical properties are compered with experimental data. Nineteen, out of 26 modes expected for the spectral region below 200cm(-1), have been observed.

Keywords: Ibuprofen; Low-temperature; Numerical calculations; Raman; Spectroscopy.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Analgesics, Non-Narcotic / chemistry*
Cold Temperature
Ibuprofen / chemistry*
Models, Molecular
Spectrum Analysis, Raman / methods

Substances

Analgesics, Non-Narcotic
Ibuprofen