Portuguese community pharmacists' attitudes to and knowledge of antibiotic misuse: questionnaire development and reliability

PLoS One. 2014 Mar 5;9(3):e90470. doi: 10.1371/journal.pone.0090470. eCollection 2014.

Abstract

Objective: To develop and evaluate the reliability of a self-administered questionnaire designed to assess the attitudes and knowledge of community pharmacists in Portugal about microbial resistance and the antibiotic dispensing process.

Methods: This study was divided into the following three stages: (1) design of the questionnaire, which included a literature review and a qualitative study with focus-group sessions; (2) assessment of face and content validity, using a panel of experts and a pre-test of community pharmacists; and, (3) pilot study and reliability analysis, which included a test-retest study covering fifty practising pharmacists based at community pharmacies in five districts situated in Northern Portugal. Questionnaire reproducibility was quantified using the intraclass correlation coefficient (ICC; 95% confidence interval) computed by means of one-way analysis of variance (ANOVA). Internal consistency was evaluated using Cronbach's alpha.

Results: The correlation coefficients were fair to good (ICC>0.4) for all statements (scale-items) regarding knowledge of and attitudes to antibiotic resistance, and ranged from fair to good to excellent for statements about situations in which pharmacists acknowledged that antibiotics were sometimes dispensed without a medical prescription (ICC>0.8). Cronbach's alpha for this section was 0.716.

Conclusions: The questionnaire designed in this study is valid and reliable in terms of content validity, face validity and reproducibility.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / therapeutic use*
  • Health Knowledge, Attitudes, Practice*
  • Humans
  • Pharmacies
  • Pharmacists*
  • Pilot Projects
  • Portugal
  • Reproducibility of Results
  • Surveys and Questionnaires*

Substances

  • Anti-Bacterial Agents

Grants and funding

This work was supported by Foundation for Science & Technology (Fundação para a Ciência e Tecnologia - FCT) grants [PTDC/SAU-ESA/105530/2008] and [Pest-OE/EGE/UI4056/2014] from the Portuguese Ministry of Science & Education. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.