Bi(OTf)3-catalyzed three-component synthesis of α-amino acid derivatives

Org Biomol Chem. 2014 Apr 21;12(15):2356-9. doi: 10.1039/c4ob00265b.

Abstract

A highly efficient Bi(OTf)3-catalyzed multicomponent synthesis of arylglycines from readily available starting materials is described. The reaction proceeds under mild conditions and provides a general route to various N-protected arylglycines.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Catalysis
  • Chemistry Techniques, Synthetic
  • Glycine / chemical synthesis*
  • Glycine / chemistry*
  • Mesylates / chemistry*
  • Stereoisomerism

Substances

  • Mesylates
  • Bi(OTf)3
  • Glycine