Missed pulmonary metastasis

Asian Cardiovasc Thorac Ann. 2014 Feb;22(2):183-6. doi: 10.1177/0218492313487081. Epub 2013 Oct 11.

Abstract

Objective: To assess the rate of detection of pulmonary nodules on preoperative computed tomography, based on intraoperative palpation of non-imaged pulmonary nodules, in patients who underwent thoracotomy for metastasectomy with bimanual lung palpation.

Methods: A retrospective study carried out on all cases of pulmonary metastasectomy performed in King Faisal Specialist Hospital and Research Center over a 10-year period (2001-2011). The number of nodules detected on preoperative computed tomography by a radiologist was compared with the number of nodules identified on pathology. Resected pulmonary nodules were classified to benign or malignant. Secondary outcomes were operative approach and primary malignancy.

Results: 215 metastasectomies were performed by thoracotomy. The incidence of nodules that were not imaged preoperatively was 36% (41% of mesenchymal tumors, 28% of epithelial tumors).

Conclusion: Metastasectomy by an open approach, which affords bimanual palpation of the entire lung, discovered ipsilateral non-imaged malignant pulmonary metastases in 36% of cases (41% of mesenchymal tumors).

Keywords: Diagnostic errors; X-ray computed; lung neoplasms; pulmonary surgical procedures; radiographic image enhancement; tomography.

MeSH terms

  • Adult
  • Aged
  • Diagnostic Errors*
  • Female
  • Humans
  • Lung Neoplasms / diagnostic imaging
  • Lung Neoplasms / secondary*
  • Lung Neoplasms / surgery*
  • Male
  • Metastasectomy / methods*
  • Middle Aged
  • Multiple Pulmonary Nodules / diagnostic imaging
  • Multiple Pulmonary Nodules / secondary*
  • Multiple Pulmonary Nodules / surgery*
  • Palpation
  • Predictive Value of Tests
  • Preoperative Care
  • Retrospective Studies
  • Saudi Arabia
  • Thoracotomy*
  • Time Factors
  • Tomography, X-Ray Computed
  • Treatment Outcome
  • Young Adult