From gut to brain: bioencapsulated therapeutic protein reduces amyloid load upon oral delivery

Mol Ther. 2014 Mar;22(3):485-486. doi: 10.1038/mt.2014.13.
No abstract available

Publication types

  • Comment

MeSH terms

  • Alzheimer Disease / drug therapy*
  • Aminopeptidases / metabolism*
  • Animals
  • Apolipoproteins E / metabolism*
  • Blood-Brain Barrier / metabolism*
  • Blood-Retinal Barrier / metabolism*
  • Chloroplasts / metabolism*
  • Cholera Toxin / metabolism*
  • Dipeptidyl-Peptidases and Tripeptidyl-Peptidases / metabolism*
  • Female
  • Humans
  • Male
  • Myelin Basic Protein / metabolism*
  • Neuronal Ceroid-Lipofuscinoses / drug therapy*
  • Neuronal Ceroid-Lipofuscinoses / physiopathology*
  • Peptides / administration & dosage*
  • Plaque, Amyloid / drug therapy*
  • Serine Proteases / metabolism*
  • Tripeptidyl-Peptidase 1

Substances

  • Apolipoproteins E
  • Myelin Basic Protein
  • Peptides
  • Tripeptidyl-Peptidase 1
  • Cholera Toxin
  • Serine Proteases
  • Aminopeptidases
  • Dipeptidyl-Peptidases and Tripeptidyl-Peptidases