Antimicrobial oligo(p-phenylene-ethynylene) film deposited by resonant infrared matrix-assisted pulsed laser evaporation

Colloids Surf B Biointerfaces. 2014 Apr 1:116:786-92. doi: 10.1016/j.colsurfb.2014.01.033. Epub 2014 Feb 6.

Abstract

The antimicrobial oligomer, oligo(p-phenylene-ethynylene) (OPE), was deposited as thin films by resonant infrared matrix-assisted pulsed laser evaporation (RIR-MAPLE) on solid substrates and exhibited light-induced biocidal activity. The biocidal activity of OPE thin films deposited by spin-coating and drop-casting was also investigated for comparison. Enhanced bacterial attachment and biocidal efficiency of the film deposited by RIR-MAPLE were observed and attributed to nanoscale surface topography of the thin film.

Keywords: Antimicrobial film; Oligo(p-phenylene-ethynylene); Resonant infrared matrix-assisted pulsed laser evaporation.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Alkynes / chemistry
  • Alkynes / pharmacology*
  • Anti-Bacterial Agents / chemistry
  • Anti-Bacterial Agents / pharmacology*
  • Dose-Response Relationship, Drug
  • Escherichia coli K12 / drug effects*
  • Ethers / chemistry
  • Ethers / pharmacology*
  • Lasers*
  • Microbial Sensitivity Tests
  • Structure-Activity Relationship

Substances

  • Alkynes
  • Anti-Bacterial Agents
  • Ethers
  • phenyleneethynylene