Hepatocellular carcinoma: diagnosis, management, and prognosis

Andrew J Page; David C Cosgrove; Benjamin Philosophe; Timothy M Pawlik

doi:10.1016/j.soc.2013.10.006

Hepatocellular carcinoma: diagnosis, management, and prognosis

Surg Oncol Clin N Am. 2014 Apr;23(2):289-311. doi: 10.1016/j.soc.2013.10.006. Epub 2013 Dec 7.

Authors

Andrew J Page¹, David C Cosgrove², Benjamin Philosophe¹, Timothy M Pawlik³

Affiliations

¹ Department of Surgery, Johns Hopkins Hospital, 600 North Wolfe Street, Baltimore, MD 21287, USA.
² Department of Medical Oncology, Johns Hopkins Hospital, 600 North Wolfe Street, Baltimore, MD 21287, USA.
³ Division of Surgical Oncology, Department of Surgery, Johns Hopkins Hospital, 600 North Wolfe Street, Blalock 688, Baltimore, MD 21287, USA. Electronic address: tpawlik1@jhmi.edu.

PMID: 24560111
DOI: 10.1016/j.soc.2013.10.006

Abstract

The successful management of hepatocellular carcinoma (HCC) requires a multidisciplinary approach, incorporating hepatologists, oncologists, surgical oncologists, transplant surgeons, and radiologists. With improvements in technology and better long-term outcomes data, management strategies for HCC have become more methodical and more successful. This article focuses on some of the most critical advances relating to carcinogenesis, surveillance, and management.

Keywords: Hepatocellular carcinoma; Locoregional therapy; Sorafenib; Transarterial chemoembolization (TACE); Transplantation.

Publication types

Review

MeSH terms

Carcinoma, Hepatocellular / diagnosis*
Carcinoma, Hepatocellular / therapy
Humans
Liver Neoplasms / diagnosis*
Liver Neoplasms / therapy
Prognosis