Vaccine effectiveness in preventing laboratory-confirmed influenza in Navarre, Spain: 2013/14 mid-season analysis

Euro Surveill. 2014 Feb 13;19(6):20700. doi: 10.2807/1560-7917.es2014.19.6.20700.

Abstract

We estimate mid-2013/14 season vaccine effectiveness (VE) of the influenza trivalent vaccine in Navarre, Spain. Influenza-like illness cases attended in hospital (n=431) and primary healthcare (n=344) were included. The overall adjusted VE in preventing laboratory-confirmed influenza was 24% (95% CI: -14 to 50). The VE was 40% (95% CI: -12 to 68) against influenza A(H1)pdm09 and 13% (95% CI: -36 to 45) against influenza A(H3). These results suggest a moderate preventive effect against influenza A(H1)pdm09 and low protection against influenza A(H3).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Case-Control Studies
  • Child
  • Child, Preschool
  • Disease Outbreaks / prevention & control*
  • Female
  • Hospitalization / statistics & numerical data
  • Humans
  • Incidence
  • Infant
  • Influenza A Virus, H1N1 Subtype / immunology*
  • Influenza Vaccines / immunology*
  • Influenza Vaccines / therapeutic use
  • Influenza, Human / epidemiology
  • Influenza, Human / immunology
  • Influenza, Human / prevention & control*
  • Influenza, Human / virology
  • Laboratories
  • Logistic Models
  • Male
  • Middle Aged
  • Primary Health Care
  • Seasons
  • Sentinel Surveillance
  • Spain / epidemiology
  • Treatment Outcome
  • Vaccination / statistics & numerical data
  • Young Adult

Substances

  • Influenza Vaccines