An association of leishmaniasis and dyserythropoiesis in children

Indian J Hematol Blood Transfus. 2014 Mar;30(1):19-21. doi: 10.1007/s12288-012-0189-0. Epub 2012 Oct 9.

Abstract

Visceral leishmaniasis results in hematological problems such as cytopenias and coagulopathies. This disorder also has morphological effects on the bone marrow. Dyserythropoiesis is one of the most prominent seen with changes like multilobed nuclear cells and the appearance of bridges between nuclei and cytoplasms. Approximately half of the children with leishmaniasis showed dyserythropoietic findings in bone marrow aspirate slides. Because this in endemic regions, physicians of these countries must be alert to correctly diagnose disease and discriminate from other dyserythropoietic disorders.

Keywords: Children; Dyserythropoiesis; Leishmaniasis.