Bioactive natural compounds from the mangrove endophytic fungi

Mini Rev Med Chem. 2014 Apr;14(4):370-91. doi: 10.2174/1389557514666140220122829.

Abstract

In recent years, mangrove endophytic fungi are increasingly attracting attention of the pharmaceutical community as they produce a wide variety of metabolites that are structurally unique and pharmacologically active. Previous chemical investigation of mangrove fungi resulted in the discovery of various bioactive secondary metabolites including terpenes, chromones, coumarins, polyketides, alkaloids and peptides with diverse structural features. The present report reviews the papers, which have appeared in the literature till now, concerning the isolation, structural elucidation, and biological activities of the secondary metabolites from mangrove endophytic fungi.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Alkaloids / chemistry
  • Alkaloids / isolation & purification
  • Alkaloids / pharmacology
  • Animals
  • Apoptosis / drug effects
  • Biological Products / chemistry*
  • Biological Products / isolation & purification
  • Biological Products / pharmacology
  • Chromones / chemistry
  • Chromones / isolation & purification
  • Chromones / pharmacology
  • Coumarins / chemistry
  • Coumarins / isolation & purification
  • Coumarins / pharmacology
  • Fungi / chemistry*
  • Fungi / metabolism
  • Humans
  • Peptides / chemistry
  • Peptides / isolation & purification
  • Peptides / pharmacology
  • Polyketides / chemistry
  • Polyketides / isolation & purification
  • Polyketides / pharmacology
  • Terpenes / chemistry
  • Terpenes / isolation & purification
  • Terpenes / pharmacology

Substances

  • Alkaloids
  • Biological Products
  • Chromones
  • Coumarins
  • Peptides
  • Polyketides
  • Terpenes
  • coumarin