Abstract
A new aromatic glycoside (1) was isolated from the roots of Glehnia littoralis Fr. Schmidtex Miq. Its structure was elucidated as vanillic acid 1-O-[β-D-apiofuranosyl-(1 → 6)-β-D-glucopyranoside] ester mainly by analysing the NMR and MS spectral data. In the in vitro assays, compound 1 displayed some TNF-α secretion inhibitory activity.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Apiaceae / chemistry*
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Drugs, Chinese Herbal / chemistry
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Drugs, Chinese Herbal / isolation & purification*
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Drugs, Chinese Herbal / pharmacology
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Glycosides / chemistry
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Glycosides / isolation & purification*
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Glycosides / pharmacology
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Nuclear Magnetic Resonance, Biomolecular
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Plant Roots / chemistry
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Tumor Necrosis Factor-alpha / antagonists & inhibitors
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Tumor Necrosis Factor-alpha / metabolism
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Vanillic Acid / analogs & derivatives*
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Vanillic Acid / chemistry
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Vanillic Acid / isolation & purification
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Vanillic Acid / pharmacology
Substances
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Drugs, Chinese Herbal
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Glycosides
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Tumor Necrosis Factor-alpha
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vanillic acid 1-O-(beta-D-apiofuranosyl-(1-6)-beta-D-glucopyranoside) ester
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Vanillic Acid