Central neurogenic hyperventilation and renal tubular acidosis in children with pontine gliomas

Neurology. 2014 Mar 25;82(12):1099-100. doi: 10.1212/WNL.0000000000000252. Epub 2014 Feb 14.

Abstract

Central neurogenic hyperventilation (CNH) is a rare neurologic condition that develops secondary to brainstem involvement. Approximately 35 noncomatose patients with CNH have been reported, including 7 with either a diffuse (patients 2–10 in the table) or focal (patient 1 in the table) brainstem glioma.1–7 Although diffuse intrinsic pontine glioma (DIPG) is the most common pediatric brainstem cancer, only 1 case report described a child with DIPG who experienced CNH.6

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acidosis, Renal Tubular / etiology
  • Acidosis, Renal Tubular / physiopathology*
  • Acidosis, Renal Tubular / therapy
  • Adolescent
  • Brain Stem Neoplasms / complications
  • Brain Stem Neoplasms / pathology*
  • Brain Stem Neoplasms / radiotherapy
  • Child
  • Female
  • Glioma / complications
  • Glioma / pathology*
  • Glioma / radiotherapy
  • Humans
  • Hyperventilation / etiology
  • Hyperventilation / physiopathology*
  • Hyperventilation / therapy
  • Male
  • Pons / pathology*
  • Retrospective Studies
  • Treatment Outcome