The anatomy of the aging aorta

Clin Anat. 2014 Apr;27(3):463-6. doi: 10.1002/ca.22384. Epub 2014 Feb 12.

Abstract

Age-associated changes to aortic anatomy and physiology have an effect on hemodynamics and play a large role in the genesis of cardiovascular pathologies including atherosclerosis, congestive heart failure, and aortic aneurysm. Despite their recognized role in hemodynamics, the complete mechanism for aortic aging is still not clear and their full effects on cardiovascular pathologies are unknown. This article serves as a review of the normal anatomy of the human aorta and its known age-associated changes.

Keywords: aging; blood vessels; circulation; geriatrics; stenosis.

Publication types

  • Review

MeSH terms

  • Aged
  • Aging / pathology*
  • Aging / physiology
  • Aorta / pathology*
  • Aorta / physiopathology
  • Aortic Valve / pathology
  • Hemodynamics
  • Humans
  • Organ Size
  • Tunica Intima
  • Vascular Calcification / pathology