Intakes of potassium, magnesium, and calcium and risk of stroke

Stroke. 2014 Apr;45(4):1148-50. doi: 10.1161/STROKEAHA.113.004032. Epub 2014 Feb 11.

Abstract

Background and purpose: We aimed to investigate the associations of dietary and total potassium, magnesium, and calcium intakes with stroke occurrence.

Methods: A prospective cohort study was conducted among 36 094 participants aged 21 to 70 years. Dietary intake was assessed with a food frequency questionnaire.

Results: During 12 years of follow-up, 631 strokes occurred. After adjustment for confounders, magnesium intake was associated with reduced stroke risk (hazard ratio [95% confidence interval] per 100 mg/d, 0.80 [0.67-0.97] dietary magnesium; 0.78 [0.65-0.93] total magnesium). Potassium and calcium intakes were not associated with stroke.

Conclusions: This study supports an association between high magnesium intake and a reduced stroke risk.

Keywords: calcium; magnesium; potassium; stroke.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Calcium, Dietary / administration & dosage*
  • Female
  • Follow-Up Studies
  • Humans
  • Incidence
  • Magnesium / administration & dosage*
  • Male
  • Middle Aged
  • Nutrition Assessment
  • Potassium, Dietary / administration & dosage*
  • Proportional Hazards Models
  • Prospective Studies
  • Risk Factors
  • Risk Reduction Behavior
  • Stroke / diet therapy*
  • Stroke / epidemiology*
  • Stroke / prevention & control
  • Young Adult

Substances

  • Calcium, Dietary
  • Potassium, Dietary
  • Magnesium