Engaging a senescent response to cure leukemia

Nat Med. 2014 Feb;20(2):123-4. doi: 10.1038/nm.3469.
No abstract available

Publication types

  • News
  • Comment

MeSH terms

  • Animals
  • Humans
  • Leukemia, Promyelocytic, Acute / drug therapy*
  • Nuclear Proteins / metabolism*
  • Promyelocytic Leukemia Protein
  • Receptors, Retinoic Acid / metabolism*
  • Recombinant Fusion Proteins / pharmacology*
  • Retinoic Acid Receptor alpha
  • Signal Transduction / physiology*
  • Transcription Factors / metabolism*
  • Tretinoin / pharmacology*
  • Tumor Suppressor Protein p53 / metabolism*
  • Tumor Suppressor Proteins / metabolism*

Substances

  • Nuclear Proteins
  • Pml protein, mouse
  • Promyelocytic Leukemia Protein
  • RARA protein, human
  • Rara protein, mouse
  • Receptors, Retinoic Acid
  • Recombinant Fusion Proteins
  • Retinoic Acid Receptor alpha
  • Transcription Factors
  • Tumor Suppressor Protein p53
  • Tumor Suppressor Proteins
  • Tretinoin