[New antiplatelet drugs in coronary artery disease]

Abstract

The dual antiplatelet therapy with acetylsalicylic acid and clopidogrel has been the mainstay of both acute and chronic phase coronary artery disease, reducing importantly the risk of adverse events. Despite a correct compliance, a non-negligible rate of adverse events still happens. New compounds, with improved properties, are now clinically available (such as prasugrel or ticagrelor) or under advanced development. The aim of the present review is the description of these new compounds, particularly prasugrel and ticagrelor.

Keywords: Antiplatelet drugs; Cardiopatía isquémica; Coronary artery disease; Fármacos antiplaquetarios; Intervencionismo coronario percutáneo; Percutaneous coronary interventions.