Skeletal metastasis is common in patients with malignancy, but very few patients have acrometastasis, that is, metastasis to the hand or foot. We present 2 cases of acrometastasis from lung cancer where primary and metastatic foci were demonstrated on FDG-PET. The first case involves a 53-year-old man who complained of left foot pain and had osteolytic metastasis in the left calcaneus due to lung adenocarcinoma. True whole-body PET demonstrated lung cancer with calcaneal metastasis. Another case involves a 62-year-old man with large cell carcinoma of the right lung who complained of right wrist pain. Osteolytic metastasis of the hamate was demonstrated on images.