Osteolytic femoral lesion detected by sonography in a case of light chain deposition disease

J Clin Ultrasound. 2014 Sep;42(7):444-8. doi: 10.1002/jcu.22129. Epub 2014 Jan 22.

Abstract

We describe a case of light chain deposition disease presenting as worsening of renal failure with a lytic femoral bone lesion discovered by sonography. Although sonography cannot be considered to be the test of choice in evaluating multiple myeloma, this technique may allow the detection and the biopsy of osteolytic bone lesions, particularly in accessible locations. Differential diagnosis is discussed.

Keywords: bones; light chain deposition disease; multiple myeloma; musculoskeletal system; ultrasonography.

Publication types

  • Case Reports

MeSH terms

  • Bone Diseases / diagnostic imaging*
  • Bone Diseases / etiology
  • Bone Diseases / metabolism
  • Diagnosis, Differential
  • Femur / diagnostic imaging*
  • Humans
  • Immunoglobulin Light Chains / metabolism*
  • Male
  • Middle Aged
  • Multiple Myeloma / complications
  • Multiple Myeloma / diagnostic imaging*
  • Multiple Myeloma / metabolism
  • Ultrasonography

Substances

  • Immunoglobulin Light Chains