Neurophysiological and behavioural research has linked observational practice (OP) to a mirroring mechanism encompassing the action-observation network (AON). Although, the original findings indicate that biological stimuli alone activate the AON, recent evidence has shown sensitivity to non-biological stimuli. Thus, the AON is suggested to be influenced by interacting bottom-up and top-down processes. In this review, we describe the multi-functional properties of the AON and discuss the implications for OP and subsequent motor learning.