A multicentric study regarding the use of hormone therapy during female mid-age (REDLINC VI)

Climacteric. 2014 Aug;17(4):433-41. doi: 10.3109/13697137.2014.882305. Epub 2014 Jan 29.

Abstract

Background: Menopausal hormone therapy (HT) has shown benefits for women; however, associated drawbacks (i.e. risks, costs, fears) have currently determined its low use.

Objective: To determine the prevalence of current HT use among mid-aged women and describe the characteristics of those who have never used, have abandoned or are currently using HT. In addition, reasons for not using HT were analyzed.

Method: This was a cross-sectional study that analyzed a total of 6731 otherwise healthy women (45-59 years old) of 15 cities in 11 Latin American countries. Participants were requested to fill out the Menopause Rating Scale (MRS) and a questionnaire containing sociodemographic data and items regarding the menopause and HT use.

Results: The prevalence of current HT use was 12.5%. Oral HT (43.7%) was the most frequently used type of HT, followed by transdermal types (17.7%). The main factors related to the current use of HT included: positive perceptions regarding HT (odds ratio (OR) 11.53, 95% confidence interval (CI) 9.41-14.13), being postmenopausal (OR 3.47, 95% CI 2.75-4.36) and having a better socioeconomic level. A total of 48.8% of surveyed women had used HT in the past, but abandoned it due to symptom improvement or being unconcerned; fear of cancer or any other secondary effects were also reported but in less than 10%. Among women who had never used HT, 28% reported the lack of medical prescription as the main reason, followed by the absence of symptoms (27.8%). Among those reporting lack of prescription as the main reason for not using HT, 30.6% currently had severe menopausal symptoms (total MRS score > 16); 19.5% of women were using alternative 'natural' therapies, with 35.1% of them displaying severe menopausal symptoms as compared to a 22.5% observed among current HT users.

Conclusion: The use of HT has not regained the rates observed a decade ago. Positive perceptions regarding HT were related to a higher use. Lack of medical prescription was the main reason for not using HT among non-users, many of whom were currently displaying severe menopausal symptoms.

Keywords: HORMONE REPLACEMENT THERAPY; MENOPAUSE; MENOPAUSE RATING SCALE; PERCEPTIONS; SYMPTOMS; USE.

Publication types

  • Multicenter Study

MeSH terms

  • Confidence Intervals
  • Cross-Sectional Studies
  • Demography
  • Estrogen Replacement Therapy* / economics
  • Estrogen Replacement Therapy* / methods
  • Estrogen Replacement Therapy* / psychology
  • Estrogen Replacement Therapy* / statistics & numerical data
  • Fear
  • Female
  • Hot Flashes* / epidemiology
  • Hot Flashes* / etiology
  • Hot Flashes* / physiopathology
  • Hot Flashes* / prevention & control
  • Hot Flashes* / psychology
  • Humans
  • Latin America
  • Menopause / psychology
  • Middle Aged
  • Needs Assessment
  • Odds Ratio
  • Practice Patterns, Physicians' / statistics & numerical data*
  • Prevalence
  • Quality of Life
  • Risk Assessment
  • Socioeconomic Factors
  • Surveys and Questionnaires
  • Treatment Refusal* / psychology
  • Treatment Refusal* / statistics & numerical data
  • Women's Health