In the past twenty years, with the rapid development of dry eye research in China, significant progresses have been achieved and there has been a remarkable improvement in diagnostic rate and clinical outcomes. Publication and popularization of the clinical diagnosis and treatment recommendations for dry eye from consensus of expert advice provides criteria for clinical work of dry eye. There has still been a significant gap between our research and world's advanced level in dry eye, therefore clinical investigations of high level will be intensively promoted to reveal the epidemiologic and clinical characteristics of dry eye populations in China, and establish the diagnostic criteria for Chinese patients, develop the clinical research on dry eye drugs and home-made clinical devices. Based on evidence-based research evidences, criteria for diagnosis and treatment of dry eye will be established and the clinical investigation of dry eye will be developed to reach the world's advanced level.