High-power electron beam tests of a liquid-lithium target and characterization study of (7)Li(p,n) near-threshold neutrons for accelerator-based boron neutron capture therapy

Appl Radiat Isot. 2014 Jun:88:238-42. doi: 10.1016/j.apradiso.2013.11.043. Epub 2013 Dec 1.

Abstract

A compact Liquid-Lithium Target (LiLiT) was built and tested with a high-power electron gun at Soreq Nuclear Research Center (SNRC). The target is intended to demonstrate liquid-lithium target capabilities to constitute an accelerator-based intense neutron source for Boron Neutron Capture Therapy (BNCT) in hospitals. The lithium target will produce neutrons through the (7)Li(p,n)(7)Be reaction and it will overcome the major problem of removing the thermal power >5kW generated by high-intensity proton beams, necessary for sufficient therapeutic neutron flux. In preliminary experiments liquid lithium was flown through the target loop and generated a stable jet on the concave supporting wall. Electron beam irradiation demonstrated that the liquid-lithium target can dissipate electron power densities of more than 4kW/cm(2) and volumetric power density around 2MW/cm(3) at a lithium flow of ~4m/s, while maintaining stable temperature and vacuum conditions. These power densities correspond to a narrow (σ=~2mm) 1.91MeV, 3mA proton beam. A high-intensity proton beam irradiation (1.91-2.5MeV, 2mA) is being commissioned at the SARAF (Soreq Applied Research Accelerator Facility) superconducting linear accelerator. In order to determine the conditions of LiLiT proton irradiation for BNCT and to tailor the neutron energy spectrum, a characterization of near threshold (~1.91MeV) (7)Li(p,n) neutrons is in progress based on Monte-Carlo (MCNP and Geant4) simulation and on low-intensity experiments with solid LiF targets. In-phantom dosimetry measurements are performed using special designed dosimeters based on CR-39 track detectors.

Keywords: Accelerator-based BNCT; Liquid-lithium; Target.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Boron Neutron Capture Therapy / instrumentation*
  • Computer Simulation
  • Equipment Design
  • Equipment Failure Analysis
  • Isotopes / chemistry
  • Isotopes / radiation effects
  • Lithium / chemistry
  • Lithium / radiation effects*
  • Models, Statistical*
  • Neutrons*
  • Particle Accelerators / instrumentation*
  • Radiometry
  • Radiotherapy Dosage
  • Radiotherapy, High-Energy / instrumentation*
  • Radiotherapy, High-Energy / methods
  • Scattering, Radiation
  • Solutions

Substances

  • Isotopes
  • Solutions
  • Lithium