ALDH1 activity identifies tumor-initiating cells and links to chromosomal instability signatures in multiple myeloma

Leukemia. 2014 May;28(5):1155-8. doi: 10.1038/leu.2013.383. Epub 2013 Dec 24.

Authors

W Zhou¹, Y Yang¹, Z Gu¹, H Wang¹, J Xia¹, X Wu², X Zhan³, D Levasseur¹, Y Zhou¹, S Janz⁴, G Tricot¹, J Shi², F Zhan¹

Affiliations

¹ Department of Internal Medicine, University of Iowa, Carver College of Medicine, Iowa City, IA, USA.
² Department of Hematology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
³ Vanderbilt University, Nashville, TN, USA.
⁴ Department of Pathology, University of Iowa, Carver College of Medicine, Iowa City, IA, USA.

No abstract available

Publication types

Letter
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

MeSH terms

Aldehyde Dehydrogenase 1 Family
Animals
Cell Line, Tumor
Chromosomal Instability*
Humans
Isoenzymes / metabolism*
Mice
Multiple Myeloma / enzymology*
Multiple Myeloma / genetics
Multiple Myeloma / pathology
Retinal Dehydrogenase / metabolism*

Substances

Isoenzymes
Aldehyde Dehydrogenase 1 Family
ALDH1A1 protein, human
ALDH1A1 protein, mouse
Retinal Dehydrogenase

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