The cGMP signaling pathway as a therapeutic target in heart failure with preserved ejection fraction

J Am Heart Assoc. 2013 Dec 11;2(6):e000536. doi: 10.1161/JAHA.113.000536.
No abstract available

Keywords: cGMP; heart failure; phosphodiesterase 5; preserved ejection fraction; soluble guanylate cyclase.

Publication types

  • Review

MeSH terms

  • Animals
  • Cardiovascular Agents / therapeutic use*
  • Cyclic GMP / metabolism*
  • Drug Design
  • Heart Failure / drug therapy*
  • Heart Failure / metabolism
  • Heart Failure / physiopathology
  • Humans
  • Molecular Targeted Therapy*
  • Second Messenger Systems / drug effects*
  • Stroke Volume*
  • Ventricular Function, Left / drug effects*

Substances

  • Cardiovascular Agents
  • Cyclic GMP