Statistical shape and appearance models of bones

Nazli Sarkalkan; Harrie Weinans; Amir A Zadpoor

doi:10.1016/j.bone.2013.12.006

Statistical shape and appearance models of bones

Bone. 2014 Mar:60:129-40. doi: 10.1016/j.bone.2013.12.006. Epub 2013 Dec 12.

Authors

Nazli Sarkalkan¹, Harrie Weinans², Amir A Zadpoor³

Affiliations

¹ Department of Biomechanical Engineering, Delft University of Technology (TU Delft), Mekelweg 2, 2628 CD Delft, The Netherlands.
² Department of Biomechanical Engineering, Delft University of Technology (TU Delft), Mekelweg 2, 2628 CD Delft, The Netherlands; Department of Orthopedics & Department of Rheumatology, UMC Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands.
³ Department of Biomechanical Engineering, Delft University of Technology (TU Delft), Mekelweg 2, 2628 CD Delft, The Netherlands. Electronic address: a.a.zadpoor@tudelft.nl.

PMID: 24334169
DOI: 10.1016/j.bone.2013.12.006

Abstract

When applied to bones, statistical shape models (SSM) and statistical appearance models (SAM) respectively describe the mean shape and mean density distribution of bones within a certain population as well as the main modes of variations of shape and density distribution from their mean values. The availability of this quantitative information regarding the detailed anatomy of bones provides new opportunities for diagnosis, evaluation, and treatment of skeletal diseases. The potential of SSM and SAM has been recently recognized within the bone research community. For example, these models have been applied for studying the effects of bone shape on the etiology of osteoarthritis, improving the accuracy of clinical osteoporotic fracture prediction techniques, design of orthopedic implants, and surgery planning. This paper reviews the main concepts, methods, and applications of SSM and SAM as applied to bone.

Keywords: Biomechanical modeling; Bone shape and density distribution; Image processing; Patient-specific models; Statistical models.

MeSH terms

Bone and Bones / diagnostic imaging
Bone and Bones / pathology*
Finite Element Analysis
Humans
Models, Anatomic*
Models, Statistical*
Radiography