Palliative treatment of the advanced gastric cancer by means of surgery and HIPEC

Bratisl Lek Listy. 2013;114(12):735-9. doi: 10.4149/bll_2013_154.

Abstract

Objectives: We demonstrate a case report of the patient who suffered from advanced gastric cancer and was treated by means of surgery and HIPEC.

Background: Gastric cancer is a therapeutic challenge in the European countries due to late diagnosis, advanced stages of the disease in time of diagnosis and early recurrence in cases where a radical surgery is possible.

Method: The patient with an advanced gastric cancer (pT3N2M1 - peritoneal and ovarian metastases) was treated by means of radical surgery in combination with hyperthermic intraoperative intraperitoneal chemotherapy (HIPEC) and early postoperative intraperitoneal chemotherapy (EPIC). Surgical treatment was followed by a standard chemotherapy. Due to recurrence, there was the second look surgery one year later again with HIPEC procedure.

Results: Patient survived 32 months after diagnosis and despite intraperitoneal recurrence she never developed clinically significant ascites and she never suffered from intestinal obstruction.

Conclusion: This case demonstrate a potential benefit of new oncosurgical approach -radical surgery + HIPEC + EPIC in the treatment of gastric cancers (Tab. 2, Fig. 6, Graph 4, Ref. 18). Text in PDF www.elis.sk.

Keywords: gastric cancer, HIPEC, EPIC, radical surgery, peritoneal cytology..

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antineoplastic Agents / administration & dosage*
  • Fatal Outcome
  • Female
  • Follow-Up Studies
  • Gastrectomy / methods*
  • Humans
  • Hyperthermia, Induced / methods*
  • Injections, Intraperitoneal
  • Intraoperative Period
  • Neoplasm Staging
  • Palliative Care / methods*
  • Stomach Neoplasms / diagnosis
  • Stomach Neoplasms / therapy*

Substances

  • Antineoplastic Agents