Acute disseminated encephalomyelitis presenting with hypertensive emergency

J Trop Pediatr. 2014 Apr;60(2):171-3. doi: 10.1093/tropej/fmt102. Epub 2013 Dec 10.

Abstract

We report a 12-year-old girl presenting with acute disseminated encephalomyelitis (ADEM) along with hypertensive emergency. Hypertension persisted for few weeks following recovery and subsided with oral clonidine. Although autonomic instability in ADEM has been reported before, hypertensive emergency was not previously documented as presenting feature of ADEM.

Keywords: ADEM; CNS; clonidine; demyelination; emergency; hypertension.

MeSH terms

  • Antihypertensive Agents / therapeutic use
  • Child
  • Clonidine / therapeutic use
  • Diagnosis, Differential
  • Encephalomyelitis, Acute Disseminated / cerebrospinal fluid
  • Encephalomyelitis, Acute Disseminated / diagnosis*
  • Encephalomyelitis, Acute Disseminated / physiopathology
  • Female
  • Humans
  • Hypertensive Encephalopathy / diagnosis
  • Hypertensive Encephalopathy / drug therapy*
  • Prednisolone / administration & dosage
  • Prednisolone / analogs & derivatives
  • Severity of Illness Index
  • Treatment Outcome

Substances

  • Antihypertensive Agents
  • methyl prednisolonate
  • Prednisolone
  • Clonidine