Superior mesenteric artery blood flow velocities following medical treatment of a patent ductus arteriosus

J Pediatr. 2014 Mar;164(3):661-3. doi: 10.1016/j.jpeds.2013.11.002. Epub 2013 Dec 8.

Abstract

We examined superior mesenteric artery blood flow velocity in response to feeding in infants randomized to trophic feeds (n = 16) or nil per os (n = 18) during previous treatment for patent ductus arteriosus. Blood flow velocity increased earlier in the fed infants, but was similar in the 2 groups at 30 minutes after feeding.

Trial registration: ClinicalTrials.gov NCT00728117.

Publication types

  • Multicenter Study
  • Randomized Controlled Trial
  • Research Support, N.I.H., Extramural

MeSH terms

  • Blood Flow Velocity*
  • Cyclooxygenase Inhibitors / therapeutic use
  • Ductus Arteriosus, Patent / drug therapy*
  • Enteral Nutrition
  • Female
  • Humans
  • Ibuprofen / therapeutic use
  • Indomethacin / therapeutic use
  • Infant, Newborn
  • Infant, Premature
  • Infant, Very Low Birth Weight
  • Male
  • Mesenteric Artery, Superior / diagnostic imaging*
  • Mesenteric Artery, Superior / physiology
  • Ultrasonography, Doppler

Substances

  • Cyclooxygenase Inhibitors
  • Ibuprofen
  • Indomethacin

Associated data

  • ClinicalTrials.gov/NCT00728117