Isomerization of Asp7 leads to increased toxic effect of amyloid-β42 on human neuronal cells

Cell Death Dis. 2013 Nov 28;4(11):e939. doi: 10.1038/cddis.2013.492.

Authors

V A Mitkevich¹, I Y Petrushanko, Y E Yegorov, O V Simonenko, K S Vishnyakova, A A Kulikova, P O Tsvetkov, A A Makarov, S A Kozin

Affiliation

¹ Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Vavilov Street 32, Moscow 119991, Russia.

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Amyloid beta-Peptides / pharmacology*
Animals
Apoptosis / drug effects
Cell Line
Humans
Membrane Potential, Mitochondrial / drug effects
Mice
Mice, Transgenic
Neurons / cytology*
Neurons / drug effects*

Substances

Amyloid beta-Peptides