Bisphosphonate-induced atypical subtrochanteric femoral fracture

BMJ Case Rep. 2013 Nov 28:2013:bcr2013201931. doi: 10.1136/bcr-2013-201931.

Abstract

The use of bisphosphonates (BPs) is universally accepted in the management of osteoporosis. However, a small percentage of patients have been recognised to develop atypical subtrochanteric fractures of the femur with the prolonged use of BPs. We report a rare case of bilateral insufficiency lesions in the proximal femora, where a major subtrochanteric fracture developed with a minor fall. This was successfully treated with internal fixation using proximal femoral nail.

Publication types

  • Case Reports

MeSH terms

  • Absorptiometry, Photon
  • Alendronate / adverse effects*
  • Bone Density Conservation Agents / adverse effects*
  • Diagnosis, Differential
  • Female
  • Fracture Fixation, Internal / methods*
  • Hip Fractures / chemically induced*
  • Hip Fractures / diagnostic imaging
  • Hip Fractures / surgery*
  • Humans
  • Middle Aged
  • Osteoporosis / drug therapy*

Substances

  • Bone Density Conservation Agents
  • Alendronate