Should vitamin D supplementation be a regular part of asthma care?

Bruce R Gordon

doi:10.1016/j.otc.2013.08.013

Should vitamin D supplementation be a regular part of asthma care?

Otolaryngol Clin North Am. 2014 Feb;47(1):97-108. doi: 10.1016/j.otc.2013.08.013. Epub 2013 Oct 1.

Author

Bruce R Gordon¹

Affiliation

¹ Cape Cod Hospital, 27 Park Street, Hyannis, MA 02601, USA; Laryngology & Otology, Harvard University, 25 Shattuck Street, Boston, MA 02115, USA; Massachusetts Eye & Ear Infirmary, 243 Charles Street, Boston, MA 02114, USA. Electronic address: docbruce@comcast.net.

PMID: 24286683
DOI: 10.1016/j.otc.2013.08.013

Abstract

Vitamin D (vitD3) deficiency occurs frequently and has profound effects on health, especially asthma. This article examines how current knowledge of vitD3 actions and the worldwide distribution of vitD3 deficiency influences everyday clinical allergy practice. Within the limits of current knowledge, the article concisely explains the molecular nature of vitD3 actions, reviews key vitD3 research as it applies to clinical care, answers questions about the potential clinical impact of low vitD3 levels, and discusses use and safety of vitD3 supplements.

Keywords: Allergy; Asthma; Calcidiol; Calcitriol; Hypersensitivity; Immunotherapy; Vitamin D; Vitamin D3.

Publication types

Review

MeSH terms

Asthma / diagnosis
Asthma / drug therapy*
Asthma / therapy
Dietary Supplements*
Female
Follow-Up Studies
Humans
Male
Risk Assessment
Treatment Outcome
Vitamin D / therapeutic use*
Vitamin D Deficiency / diagnosis
Vitamin D Deficiency / drug therapy*

Substances

Vitamin D