Nystagmus following acute avermectins poisoning

Toxicol Ind Health. 2016 Apr;32(4):751-2. doi: 10.1177/0748233713503377. Epub 2013 Nov 26.

Abstract

Background: Acute pesticide poisoning is a major public health problem in the world. Most pesticides are toxic to human beings, because of diverse components resulting in different reaction.

Objective: As clinicians identify various symptoms due to pesticide poisoning, it is necessary for the diagnosis and treatment for treating such toxins. Accidents associated with acute avermectins poisoning are rarely reported, especially self-induced nystagmus. In the present study, a case of human abamectin poisoning with relevant toxic effects has been reported.

Conclusions: Acute avermectins poisoning-induced nystagmus may be affected due to the vestibular cerebellar system, but the exact mechanism and pharmacological basis is still worthy of further study.

Keywords: Avermectin; nystagmus; poisoning.

Publication types

  • Case Reports

MeSH terms

  • China
  • Humans
  • Ivermectin / analogs & derivatives*
  • Ivermectin / poisoning
  • Male
  • Middle Aged
  • Nystagmus, Pathologic / chemically induced*

Substances

  • Ivermectin
  • avermectin