[Adverse reactions of tanshinone II(A) sodium sulfonate injection in treating 18 cases: an analysis of clinical features]

Zhongguo Zhong Xi Yi Jie He Za Zhi. 2013 Sep;33(9):1287-9.
[Article in Chinese]

Abstract

Objective: To explore clinical features the adverse reactions of Tanshinone II(A) Sodium Sulfonate Injection (T II(A) SSI) and their reasons, thus providing reference for rational medication.

Methods: The literatures on adverse reactions and incompatibilities of T II(A) SSI were retrieved (domestic medical journals from January 2000 to December 2011) and statistically analyzed.

Results: In the 18 cases of adverse drug reaction (ADR), the clinical manifestations of T II(A) SSI induced adverse reactions were various, involving reactions of appendages and the neuromuscular system (each accounting for 50%). The elderly and women were mainly involved. Many organs and systems were involved. There existed more incompatibilities.

Conclusion: The medical workers should pay special attention to T II(A) SSI induced adverse reactions, thus avoiding recurrence of ADR, evading risks, and ensuring safe and rational medication.

Publication types

  • English Abstract

MeSH terms

  • Adult
  • Aged
  • Drug-Related Side Effects and Adverse Reactions*
  • Female
  • Humans
  • Injections
  • Male
  • Middle Aged
  • Phenanthrenes / administration & dosage
  • Phenanthrenes / adverse effects*

Substances

  • Phenanthrenes
  • tanshinone II A sodium sulfonate