Age, left atrial dimension and arterial stiffness after external cardioversion of atrial fibrillation. A vascular component in arrhythmia maintenance? Results from a preliminary study

Aging Clin Exp Res. 2014 Jun;26(3):327-30. doi: 10.1007/s40520-013-0173-z. Epub 2013 Nov 24.

Abstract

Background and aims: Atrial fibrillation (AF) is the most frequent arrhythmia in elderly patients. Aims of this study were to evaluate the predictors of arterial stiffness after external cardioversion (ECV) of AF and to establish whether a link exists between vascular properties and left atrial diameter (LAD).

Methods: We studied 33 patients (age 73 ± 12 years). After 5 h from ECV of persistent AF, an echocardiogram was recorded and arterial stiffness was evaluated with cardio-ankle vascular stiffness index (CAVI).

Results: In multivariate analysis (R = 0.538, p = 0.006), CAVI (mean 9.60 ± 1.63) increased with age (p = 0.018) and with an AF length ≤3 months (p = 0.022). LAD was significantly related to CAVI (p = 0.007) even after adjustment for interventricular septum thickness (p = 0.018) (R = 0.574, p = 0.002).

Conclusions: In patients with AF, immediately after ECV, arterial stiffness is associated with age and AF length, and could represent an important factor for left atrium remodeling and, therefore, for AF maintenance.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Aging / pathology
  • Aging / physiology
  • Atrial Fibrillation / pathology
  • Atrial Fibrillation / physiopathology*
  • Atrial Fibrillation / therapy*
  • Electric Countershock*
  • Female
  • Heart Atria / diagnostic imaging
  • Heart Atria / pathology*
  • Heart Atria / physiopathology*
  • Humans
  • Male
  • Middle Aged
  • Ultrasonography
  • Vascular Stiffness*