Diagnosis, nonsurgical management, and prevention of LVAD thrombosis

J Card Surg. 2014 Jan;29(1):83-94. doi: 10.1111/jocs.12238. Epub 2013 Nov 24.

Abstract

Left ventricular assist device (LVAD) thrombosis is a life-threatening complication. Multiple case reports describe successful nonsurgical management with thrombolytics, aggressive antiplatelet therapy, or percutaneous catheter-directed thrombectomy. However, consensus management of LVAD thrombosis has not been established and guidelines are urgently needed. In order to raise awareness of nonsurgical treatment options, we review the current strategies for the clinical diagnosis, management, and prevention of LVAD thrombosis.

Publication types

  • Review

MeSH terms

  • Heart Diseases / diagnosis*
  • Heart Diseases / prevention & control
  • Heart Diseases / therapy*
  • Heart-Assist Devices / adverse effects*
  • Humans
  • Platelet Aggregation Inhibitors / administration & dosage*
  • Practice Guidelines as Topic
  • Thrombectomy / methods*
  • Thrombosis / diagnosis*
  • Thrombosis / prevention & control
  • Thrombosis / therapy*

Substances

  • Platelet Aggregation Inhibitors