Abstract
A new synthesis of indole derivatives has been achieved through intramolecular dehydrative coupling of tertiary amines and ketones promoted by KO-t-Bu/DMF. The reaction probably proceeds via an α-amino alkyl radical pathway.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Amines / chemistry*
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Catalysis
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Combinatorial Chemistry Techniques
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Indoles / chemical synthesis*
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Indoles / chemistry
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Ketones / chemistry
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Molecular Structure