Neuromodulation for fecal incontinence: an effective surgical intervention

World J Gastroenterol. 2013 Nov 7;19(41):7048-54. doi: 10.3748/wjg.v19.i41.7048.

Abstract

Fecal incontinence is a disabling symptom with medical and social implications, including fear, embarrassment, isolation and even depression. Most patients live in seclusion and have to plan their life around the symptom, with secondary impairment of their quality of life. Conservative management and biofeedback therapy are reported to benefit a good percentage of those affected. However, surgery must be considered in the non-responder population. Recently, sacral nerve electrostimulation, lately named neuromodulation, has been reported to benefit patients with fecal incontinence in randomized controlled trials more than placebo stimulation and conservative management, by some unknown mechanism. Neuromodulation is a minimally invasive procedure with a low rate of adverse events and apparently favorable cost-efficacy profile. This review is intended to expand knowledge about this effective intervention among the non-surgically skilled community who deals with this disabled group of patients.

Keywords: Anal sphincter; Biofeedback; Fecal incontinence; Neuromodulation; Sacral nerve stimulation.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Anal Canal / innervation*
  • Animals
  • Defecation*
  • Electric Stimulation Therapy / adverse effects
  • Electric Stimulation Therapy / instrumentation
  • Electric Stimulation Therapy / methods*
  • Fecal Incontinence / diagnosis
  • Fecal Incontinence / physiopathology
  • Fecal Incontinence / psychology
  • Fecal Incontinence / surgery*
  • Humans
  • Implantable Neurostimulators
  • Lumbosacral Plexus / physiopathology*
  • Quality of Life
  • Treatment Outcome