Abstract
An 18-year-old man presented with 6 weeks' history of diplopia, early morning headaches, and blurred vision; on ophthalmologic examination, Parinaud syndrome was revealed. Brain MRI scan showed a calcified pineal mass. Brain simultaneous PET/MRI with 18F-choline showed an avid enhancing mass occupying the pineal region with restricted diffusion. A second examination after chemotherapy demonstrated reduction in both size and radiotracer activity of the mass. Our study emphasizes the potential of simultaneous 18F-choline PET/MRI being a useful tool for contribution in the diagnosis and treatment assessment in a convenient way with minimal radiation exposure and reduced throughput patient time.
MeSH terms
-
Adolescent
-
Antineoplastic Combined Chemotherapy Protocols / therapeutic use
-
Brain Neoplasms / diagnostic imaging*
-
Brain Neoplasms / drug therapy
-
Brain Neoplasms / pathology
-
Choline / analogs & derivatives
-
Cisplatin / therapeutic use
-
Cyclophosphamide / therapeutic use
-
Etoposide / therapeutic use
-
Humans
-
Magnetic Resonance Imaging
-
Male
-
Multimodal Imaging
-
Neoplasms, Germ Cell and Embryonal / diagnostic imaging*
-
Neoplasms, Germ Cell and Embryonal / drug therapy
-
Neoplasms, Germ Cell and Embryonal / pathology
-
Pineal Gland / diagnostic imaging*
-
Pineal Gland / pathology
-
Pinealoma / diagnostic imaging*
-
Pinealoma / drug therapy
-
Pinealoma / pathology
-
Positron-Emission Tomography
-
Radiopharmaceuticals
-
Treatment Outcome
Substances
-
Radiopharmaceuticals
-
fluoromethylcholine
-
Etoposide
-
Cyclophosphamide
-
Choline
-
Cisplatin