Meta-analysis of primary mesh augmentation as prophylactic measure to prevent incisional hernia

Dig Surg. 2013;30(4-6):401-9. doi: 10.1159/000355956. Epub 2013 Nov 5.

Abstract

Background: Incisional hernia (IH) remains one of the most frequent postoperative complications after abdominal surgery. As a consequence, primary mesh augmentation (PMA), a technique to strengthen the abdominal wall, has been gaining popularity. This meta-analysis was conducted to evaluate the prophylactic effect of PMA on the incidence of IH compared to primary suture (PS).

Methods: A meta-analysis was conducted according to the PRISMA guidelines. Randomized controlled trials (RCTs) comparing PMA and PS for closing the abdominal wall after surgery were included.

Results: Out of 576 papers, 5 RCTs were selected comprising 346 patients. IH occurred significantly less in the PMA group (RR 0.25, 95% CI 0.12-0.52, I(2)0%; p < 0.001). No difference could be observed with regard to wound infection (RR 0.86, 95% CI 0.39-1.91, I(2) 0%; p = 0.71) or seroma (RR 1.22, 95% CI 0.64-2.33, I(2) 0%; p = 0.55). A trend was observed for chronic pain in favor of the PS group (RR 5.95, 95% CI 0.74-48.03, I(2)0%; p = 0.09).

Conclusion: The use of PMA for abdominal wall closure is associated with significantly lower incidence of IH compared to PS.

Publication types

  • Meta-Analysis
  • Review

MeSH terms

  • Abdominal Wall / surgery
  • Adult
  • Aortic Aneurysm, Abdominal / epidemiology
  • Causality
  • Comorbidity
  • Hernia, Ventral / diagnosis
  • Hernia, Ventral / epidemiology
  • Hernia, Ventral / prevention & control*
  • Humans
  • Incidence
  • Laparotomy / methods
  • Obesity / epidemiology
  • Recurrence
  • Reoperation
  • Risk Factors
  • Surgical Mesh / statistics & numerical data*
  • Suture Techniques