Abstract
Eighty-one distinct fungal endophytes were isolated from 12 traditionally used medicinal plants from New Brunswick, Canada. This is the first report of endophytes from 8 of the 12 host plants. One hundred and sixty-two crude extracts derived from the mycelia and spent fermentation broths of liquid cultures of each endophyte were screened for antibacterial and antifungal activity. Twenty-two extracts were active against Staphylococcus aureus while 30 were active against Pseudomonas aeruginosa. Twelve crude extracts were found to be active against Candida albicans.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Anti-Bacterial Agents / isolation & purification*
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Anti-Bacterial Agents / pharmacology
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Antifungal Agents / isolation & purification*
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Antifungal Agents / pharmacology
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Biological Assay
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Candida albicans / drug effects
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Endophytes / chemistry
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Endophytes / classification
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Endophytes / isolation & purification*
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Fungi / chemistry
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Fungi / classification
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Fungi / isolation & purification*
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Microbial Sensitivity Tests
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New Brunswick
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Plants, Medicinal / microbiology*
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Pseudomonas aeruginosa / drug effects
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Staphylococcus aureus / drug effects
Substances
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Anti-Bacterial Agents
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Antifungal Agents