A Gram-staining-negative, rod-shaped and non-spore-forming bacterium, designated strain RG1-1(T), was isolated from Takakia lepidozioides collected from Gawalong glacier in Tibet, China, and characterized by using a polyphasic taxonomic approach. The predominant fatty acids of strain RG1-1(T) were iso-C(15 : 0) (19.8%), summed feature 3 (C(16 : 1)ω7c and/or C(16 : 1)ω6c, 17.0%), C(16 : 0 (9.9)%) and iso-C(17 : 0) 3-OH (9.4%); its major polar lipids were phosphatidylethanolamine, four unidentified aminolipids, one unidentified phospholipid, one unidentified aminoglycolipid, one unidentified glycolipid, and three unidentified lipids. Strain RG1-1(T) contained MK-7 as the dominant menaquinone, and the G+C content of its genomic DNA was 49.1 mol%. Strain RG1-1(T) exhibited the highest 16S rRNA gene sequence similarity (91.8%) with Flavisolibacter ginsengiterrae Gsoil 492(T) and Flavisolibacter ginsengisoli Gsoil 643(T). Phylogenetic analysis showed that strain RG1-1(T) was a member of the family Chitinophagaceae, phylum Bacteroidetes. On the basis of 16S rRNA gene sequence analysis, and phenotypic and chemotaxonomic data, strain RG1-1(T) is considered to represent a novel species of a novel genus, for which the name Cnuella takakiae gen. nov., sp. nov. is proposed. The type strain is RG1-1(T) ( = CGMCC 1.12492(T) = DSM 26897(T)).