The emerging roles of somatic globins in cardiovascular redox biology and beyond

Redox Biol. 2013 Aug 16;1(1):405-10. doi: 10.1016/j.redox.2013.08.001.

Abstract

The vertebrate globins are a group of hemoproteins with the intrinsic capacity to regulate gaseous ligands and redox signaling required for cardiovascular biology. This graphical review will provide a comprehensive synopsis of somatic cardiovascular globins focusing on expression, function and redox signaling - an emerging area in both physiology and disease.

Keywords: Cariovascular; Cytochrome b5 reductase; Cytoglobin; Globin; Hemoglobin; Myoglobin; Neuroglobi; Nitric oxide.

Publication types

  • Review

MeSH terms

  • Animals
  • Cardiovascular System / metabolism*
  • Globins / metabolism*
  • Humans
  • Oxidation-Reduction
  • Signal Transduction

Substances

  • Globins