Simplified deoxypropionate acyl chains for Mycobacterium tuberculosis sulfoglycolipid analogues: chain length is essential for high antigenicity

Chembiochem. 2013 Dec 16;14(18):2413-7. doi: 10.1002/cbic.201300482. Epub 2013 Oct 31.

Authors

Benjamin Gau¹, Aurélie Lemétais, Marco Lepore, Luis Fernando Garcia-Alles, Yann Bourdreux, Lucia Mori, Martine Gilleron, Gennaro De Libero, Germain Puzo, Jean-Marie Beau, Jacques Prandi

Affiliation

¹ Institut de Pharmacologie et de Biologie Structurale (IPBS), CNRS and Université de Toulouse, BP 64182, 205 route de Narbonne, 31077 Toulouse (France).

PMID: 24174158
DOI: 10.1002/cbic.201300482

No abstract available

Keywords: antigens; glycolipids; trehalose; tuberculosis; vaccines.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Antigens, Bacterial / chemistry
Antigens, Bacterial / immunology*
Glycolipids / chemistry
Glycolipids / immunology*
Humans
Mycobacterium tuberculosis / chemistry
Mycobacterium tuberculosis / immunology*
Trehalose
Tuberculosis / immunology
Tuberculosis / microbiology
Tuberculosis / prevention & control*
Tuberculosis Vaccines / chemistry
Tuberculosis Vaccines / immunology*

Substances

Antigens, Bacterial
Glycolipids
Tuberculosis Vaccines
sulfoglycolipids
Trehalose