Gastric xanthelasma: an unusual endoscopic finding

BMJ Case Rep. 2013 Oct 28:2013:bcr2013201017. doi: 10.1136/bcr-2013-201017.

Abstract

Gastric xanthelasma is a rarely encountered finding in upper gastrointestinal (GI) endoscopy. It is characterised by yellowish-white plaque in the stomach especially in the antrum or the pyloric region. Histologically it consists of foamy macrophages in the lamina propria. It is a benign condition but its appearance mimics malignancy and it is found to be associated with various conditions, some of which are considered premalignant so, histological confirmation is necessary. We present a case of a 44-year-old man who presented to the medicine outpatient department for intermittent pain in epigastrium for the last 2 years. His physical examination was normal. His haematological and biochemical investigations were also normal. His upper GI endoscopy revealed yellowish-white plaque in fundus of the stomach, which was diagnosed as gastric xanthelasma by histological examination with associated chronic gastritis.

Publication types

  • Case Reports
  • Review

MeSH terms

  • 2-Pyridinylmethylsulfinylbenzimidazoles / therapeutic use
  • Adult
  • Biopsy, Needle
  • Chronic Disease
  • Follow-Up Studies
  • Gastric Fundus / pathology
  • Gastritis / complications
  • Gastritis / diagnosis
  • Gastritis / pathology*
  • Gastroscopy / methods*
  • Humans
  • Immunohistochemistry
  • India
  • Male
  • Pantoprazole
  • Rare Diseases
  • Risk Assessment
  • Stomach Diseases / complications
  • Stomach Diseases / diagnosis*
  • Stomach Diseases / drug therapy
  • Stomach Diseases / pathology
  • Treatment Failure
  • Xanthomatosis / complications
  • Xanthomatosis / diagnosis*
  • Xanthomatosis / drug therapy
  • Xanthomatosis / pathology

Substances

  • 2-Pyridinylmethylsulfinylbenzimidazoles
  • Pantoprazole