An efficient one-pot synthesis of benzo[4,5]imidazo[1,2-a]quinoxalines via copper-catalyzed process

Aiping Huang; Yimu Chen; Yige Zhou; Wei Guo; Xiaodong Wu; Chen Ma

doi:10.1021/ol4026292

An efficient one-pot synthesis of benzo[4,5]imidazo[1,2-a]quinoxalines via copper-catalyzed process

Org Lett. 2013 Nov 1;15(21):5480-3. doi: 10.1021/ol4026292. Epub 2013 Oct 22.

Authors

Aiping Huang¹, Yimu Chen, Yige Zhou, Wei Guo, Xiaodong Wu, Chen Ma

Affiliation

¹ School of Chemistry and Chemical Engineering, Shandong University , Jinan, 250100, P. R. China, and State Key Laboratory of Natural and Biomimetic Drugs, Peking University , Beijing, 100191, P. R. China.

PMID: 24147823
DOI: 10.1021/ol4026292

Abstract

A copper-catalyzed one-pot process for the construction of benzo[4,5]imidazo[1,2-a]quinoxalines under air is described. Aryl chlorides, aryl bromides, and aryl iodides can be applied to the synthesis of these compounds.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Catalysis
Copper / chemistry*
Halogens / chemistry
Imidazoles / chemical synthesis*
Imidazoles / chemistry
Molecular Structure
Quinoxalines / chemical synthesis*
Quinoxalines / chemistry

Substances

Halogens
Imidazoles
Quinoxalines
Copper