Tonsillar hyperplasia and recurrent tonsillitis: clinical-histological correlation

Braz J Otorhinolaryngol. 2013 Sep-Oct;79(5):603-8. doi: 10.5935/1808-8694.20130108.
[Article in English, Portuguese]

Abstract

Hypertrophy and recurrent tonsillitis are common indications of tonsillectomy. However, the pathological reports are similar, regardless of clinical aspects.

Objective: Search for histopathological changes that differentiate palatine tonsils operated because of hypertrophy vis-à-vis those operated because of recurrent tonsillitis.

Method: A prospective cross-sectional descriptive study involving 46 children divided into group I - 22 with hypertrophy; and group II - 24 with recurrent tonsillitis, in the period between 2010 and 2012, in a public hospital. We evaluated clinical and histopathological features (lymph follicles, germinal centers, fibrosis, necrosis, reticulation, infiltration by plasma cells and neutrophils).

Results: The patients' ages ranged between 2 and 11 years (5.17 ± 2.28). In group I, half of the patients had had the latest infection at seven months or more, and all with obstruction degree greater than 3 (> 50%). In group II, all had had the latest infection at less than seven months, and most with obstruction degree below 4 (< 75%). There was a statistically significant difference in the degree of obstruction (p = 0.0021) and number of germinal centers (p = 0.002) was higher in group I.

Conclusion: This study suggests that the number of germinal centers is the only histopathological criterion that can be used to differentiate the two groups.

Publication types

  • Comparative Study

MeSH terms

  • Child
  • Child, Preschool
  • Cross-Sectional Studies
  • Female
  • Humans
  • Hyperplasia / pathology
  • Male
  • Palatine Tonsil / pathology*
  • Palatine Tonsil / surgery
  • Prospective Studies
  • Recurrence
  • Severity of Illness Index
  • Tonsillectomy
  • Tonsillitis / pathology*
  • Tonsillitis / surgery