Automatic extraction of retinal features from colour retinal images for glaucoma diagnosis: a review

Comput Med Imaging Graph. 2013 Oct-Dec;37(7-8):581-96. doi: 10.1016/j.compmedimag.2013.09.005. Epub 2013 Sep 27.

Abstract

Glaucoma is a group of eye diseases that have common traits such as, high eye pressure, damage to the Optic Nerve Head and gradual vision loss. It affects peripheral vision and eventually leads to blindness if left untreated. The current common methods of pre-diagnosis of Glaucoma include measurement of Intra-Ocular Pressure (IOP) using Tonometer, Pachymetry, Gonioscopy; which are performed manually by the clinicians. These tests are usually followed by Optic Nerve Head (ONH) Appearance examination for the confirmed diagnosis of Glaucoma. The diagnoses require regular monitoring, which is costly and time consuming. The accuracy and reliability of diagnosis is limited by the domain knowledge of different ophthalmologists. Therefore automatic diagnosis of Glaucoma attracts a lot of attention. This paper surveys the state-of-the-art of automatic extraction of anatomical features from retinal images to assist early diagnosis of the Glaucoma. We have conducted critical evaluation of the existing automatic extraction methods based on features including Optic Cup to Disc Ratio (CDR), Retinal Nerve Fibre Layer (RNFL), Peripapillary Atrophy (PPA), Neuroretinal Rim Notching, Vasculature Shift, etc., which adds value on efficient feature extraction related to Glaucoma diagnosis.

Keywords: Automatic feature detection; Feature extraction; Fundus image; Glaucoma; Retinal diseases analysis; Retinal image analysis.

Publication types

  • Review

MeSH terms

  • Algorithms*
  • Artificial Intelligence*
  • Colorimetry / methods*
  • Glaucoma / pathology*
  • Humans
  • Image Enhancement / methods
  • Image Interpretation, Computer-Assisted / methods*
  • Pattern Recognition, Automated / methods*
  • Reproducibility of Results
  • Retinoscopy / methods*
  • Sensitivity and Specificity
  • Subtraction Technique