Dual kidney transplant: a single-center experience and review of the literature

Exp Clin Transplant. 2013 Oct;11(5):388-95. doi: 10.6002/ect.2013.0040.

Abstract

Objectives: Adult dual kidney transplant is a strategy to overcome the imbalance between limited nephron mass supplied from an older donor and a recipient with a metabolic request.

Materials and methods: In our report, we review the literature and present our single-center experience. From June 2007 until July 2012, nine hundred twenty-eight single and seventeen dual kidney transplants from deceased donors were performed.

Results: The average donor was 71.5 ± 3.6 years of age with an average serum creatinine, creatinine clearance, and an average number of sclerotic glomeruli, 106.1 ± 44.2 μmol/L, 0.97 ± 0.37 mL/s, and 22.4 ± 14.2. Immediate graft function and acute rejection episodes were observed in 75% and 6% of patients. The overall patient survival rates at 1 and 2 years after transplant were 93%. The overall graft survival rates at 1 and 2 years were 88%.

Conclusions: Previous studies and our single-center experience suggest that the dual transplant procedure may help improve results of kidney transplants from expanded criteria donors and extend the donor pool by using kidneys that would be discarded otherwise.

Publication types

  • Review

MeSH terms

  • Acute Disease
  • Aged
  • Czech Republic
  • Delayed Graft Function / etiology
  • Delayed Graft Function / mortality
  • Donor Selection*
  • Female
  • Graft Rejection / etiology
  • Graft Rejection / mortality
  • Graft Survival
  • Humans
  • Kaplan-Meier Estimate
  • Kidney Transplantation / adverse effects
  • Kidney Transplantation / methods*
  • Kidney Transplantation / mortality
  • Male
  • Retrospective Studies
  • Risk Factors
  • Time Factors
  • Tissue Donors / supply & distribution*
  • Treatment Outcome