A review on novel vesicular drug delivery: proniosomes

Drug Deliv. 2014 Jun;21(4):243-9. doi: 10.3109/10717544.2013.841783. Epub 2013 Oct 16.

Abstract

Nanotechnology has brought a revolution in the field of science, which has subsequently lead to development of novel dosage forms such as niosomes, liposomes and proniosomes. Proniosomes overcome the demerits involved with niosomal and liposomal drug delivery systems. Proniosomes are liquid crystalline compact niosome hybrids which upon hydration form niosomes. They help in reducing physical stability problems involved with niosomes such as leaking, fusion, aggregation and provide convenience in dosing, distribution, transportation and storage showing improved results than conventional niosomes. This review focuses on different aspects of proniosome such as preparation, characterization, drug release, applications, merits, demerits, present scenario in market and future trends.

Keywords: Applications; characterization; drug release; niosomes; proniosomes.

Publication types

  • Review

MeSH terms

  • Animals
  • Drug Carriers / administration & dosage
  • Drug Carriers / chemistry
  • Drug Delivery Systems / methods
  • Drug Delivery Systems / trends*
  • Humans
  • Liposomes / administration & dosage
  • Liposomes / chemistry*
  • Particle Size
  • Prodrugs / administration & dosage
  • Prodrugs / chemistry*

Substances

  • Drug Carriers
  • Liposomes
  • Prodrugs