Abstract
Varenicline is a partial agonist at the α4β2 nicotinic acetylcholine receptor effective as smoking cessation pharmacotherapy. We present a familial case of severe restless legs syndrome (RLS) resistant to polytherapy who showed a consistent and effective amelioration of RLS symptoms after introduction of varenicline as antismoking drug.
Keywords:
Restless legs syndrome; nicotinic acetylcholine receptor agonist; varenicline.
MeSH terms
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Aged, 80 and over
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Benzazepines / therapeutic use*
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Dose-Response Relationship, Drug
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Drug Administration Schedule
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Female
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Follow-Up Studies
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Humans
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Nicotinic Agonists / therapeutic use*
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Patient Satisfaction
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Quinoxalines / therapeutic use*
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Restless Legs Syndrome / diagnosis*
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Restless Legs Syndrome / drug therapy*
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Severity of Illness Index
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Treatment Outcome
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Varenicline
Substances
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Benzazepines
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Nicotinic Agonists
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Quinoxalines
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Varenicline